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27, 28 A recent systematic review and meta analysis comparing the cardiotoxicity of tamoxifen versus AIs found that AIs increased the risk of CV AEs by 19 compared with tamoxifen and that tamoxifen reduced CV risk by 33 compared with placebo or no treatment maximum dose of lasix Cisplatin resistance involves a metabolic reprogramming through ROS and PGC 1alpha in NSCLC which can be overcome by OXPHOS inhibition |
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